ABSTRACT
The upper limit of normal values of group A streptococcal antibodies should be known for a population concerned because it is influenced by many local conditions. As yet the reference value of the these antibodies has not been determined by using a quantitative method among Bangladeshi children. We determined the reference value of anti-streptolysin O and anti-deoxyribonuclease B among 361 apparently healthy rural Bangladeshi primary school children (aged 5 to 14 years, mean 9.2 years). Anti-streptolysin O was measured by an auto-analyzer and antideoxyribonuclease B was measured by microtitre method. The geometric mean titres for the entire group was 241 IU/ml and 222 IU/ml for anti-streptolysin O and anti-deoxyribonuclease B respectively. The upper limit of normal values (80th percentile) was 390 and 340 for anti-streptolysin O and anti-deoxyribonuclease B, respectively. These limits should be of value to physicians, epidemiologists and clinical laboratory personnel as well.
Subject(s)
Adolescent , Antibodies, Bacterial/blood , Bacterial Proteins , Bangladesh , Child , Child, Preschool , Deoxyribonucleases/immunology , Female , Humans , Male , Reference Values , Rural Health , Streptococcus pyogenes/immunology , Streptolysins/immunologyABSTRACT
The diagnosis of coronary artery disease [CAD] on the basis of inducible wall motion abnormalities [WMA] as well as Doppler-derived indices rather than WMA alone was suggested to improve specificity of dobutamine stress echocardiography [DSE]. This study aimed to find out the impact of using these criteria together on accuracy and sensitivity of high dose [DSE] test in the evaluation of CAD. Thirty patients with chronic stable angina or old MI were classified according to the results of coronary angiography into two groups: Group I included 17 patients with a significant CAD and Group II included 13 patients with normal coronaries. The studied groups were well matched regarding basal characteristics